The patient was a four-year-old male, up-to-date with vaccinations and with no prior medical history; he did attend daycare.
- 5/31/2023: to ED (at St. Lucie)
o Mom said nausea/vomiting, cough, fever, not eating normal amount, drinking “some.” Evaluated elsewhere 5/30/2023 and given Zofran; worse today w/ 101 fever at home, worsening cough and c/o abdominal pain.
o ED vitals @ 2027: T 103.1, HR 184, RR 22, O2 89% on RA started on O2 mask
2259: T 98.5, HR 144, RR 30, O2 100% on mask
o PE:
General “NAD, cooperative, well appearing, playful”
Lungs: “Bilateral wheezes, decreased breath sounds on the right, no retractions, oxygenating in the low 90s on 3 L nasal cannula”
Abd: “Periumbilical, RLQ tendernesss, soft, no rebound, guarding, no CVA tenderness”
o Labs:
WBCs 14.9 H
Hgb 10.6 L
HCt 31.1 L
Sodium 132 L
BUN 20 H
Glucose 143 H
Negative for COVID-19, Influenza A and B, Group A Strep Screen, RSV Antigen
Blood cultures pending
o CXR Impression: “Consolidated infiltrate in the mid to upper right lung and mild mid left lung infiltrate.”
o CT Abdomen & Pelvis w/ Impression: “1. Constipation. 2. Incidentally noted is a consolidated infiltrate and atelectasis the right lung base, mild to moderate right pleural effusion, left lung densities likely infiltrates only partially included on this study. Chest imaging recommended with consideration for CT scan.”
o Dx pneumonia, hypoxemia, periumbilical pain, RLQ pain (per coding summary)
ED Primary impression at 2201: Right middle lobe pneumonia
• Secondary: Hypoxia, right upper lobe pneumonia
o “Sepsis bundle” initiated; transferred to Lawnwood to pediatric ER MD
Ceftriaxone, DuoNeb, 20 mL/kg fluid bolus
Also given acetaminophen at 2057
“Blood cultures pending” at discharge
Transfer accepted at 2208
o At some point, blood cx + for penicillin resistant Strep pneumo
Resistant to ceftriaxone, penicillin, erythromycin
Susceptible to vancomycin, levofloxacin
Notification from lab to hospital of gram positive cocci on 6/1/2023 at 2201
Notification from lab to hospital of final results on 6/3/2023 at 1331
No indication Lawnwood or patient ever told
- 5/31/2023: transferred to Lawnwood ED for pediatric ED doctor
o ED provider report @ 2334:
“… Went to St. Lucie today where patient was diagnosed with right-sided pneumonia meeting sepsis criteria and having hypoxia. Was given ceftriaxone but no azithro. Sent here for peds admit. On 2L face mask here….”
ED Vitals @ 2346: T 36.8, HR 147, RR 24, BP 117/66, O2 100% on mask
PE:
• Gen: “Well appearing/NAD”
• Abd: “Soft/non-tender”
• Resp: “No resp distress”
• Etc.
Azithromycin IV 181 mg given in ED
MDM Notes: “Patient meet sepsis criteria secondary to right-sided pneumonia. Titrated down to 2 liters nasal cannula. Will add azithromycin to cover for atypical pneumonia. Pediatric hospitalist called for admission. Patient admitted in stable condition.”
• Primary impression: Pneumonia involving right lung
• Secondary impression: Hypoxia, sepsis
- 6/1/2023:
o Nursing records:
0110: “transported via stretcher with mom at bedside and ED nurse, pt asleep with O2 via mask, no acute distress noted at this time, on RA O2 at 100%. IV on left AC patient, intact with Zithromax infusing….”
0115 Sepsis Screening:
• Temp: no
• HR: yes
• RR: yes
• WBC results / band results: “No results past 48 hrs”
• Pediatric glucose results: “No results past 48 hrs”
• Etc. -- (criteria met)
0115: Pain Assessment:
• Face: occasional grimace 1
• Activity: Lying quietly 0
• Cry: Moans or whimpers 1
• Total score: 2
• Pain location: Abdomen
• Pt on RA 100%, “pulse ox continue”
0122 Vitals: T 37.3, HR 148, RR 24, O2 100%; LOC alert
0400 Vitals: T 98.2 axillary, HR 134, RR 24, O2 100% on RA
0411: Pain assessment 0
0730 Vitals: T 38.0 oral, HR 177, RR 28, O2 100% on RA
0800 shift assessment:
• Respiratory:
o Respirations even and unlabored: No
o Respiratory effort and pattern: Accessory muscles use, shallow
o Bilateral lung sounds clear, equal and undiminished: No
o All lobes: “Snoring”
• Cough/sputum: Intermittent non productive cough
• Mouth/throat: dry, cracked lips
• Abdomen: Firm, w/ generalized/diffuse tenderness to palpation; bowel sounds active x4, passing flatus
• Everything else WNL
• Sepsis assessment same as above; positive for severe sepsis: 1 – “Dr. Freeland notified”
• Pain assessment score 2
o Admitted for observation – Peds H&P:
Time 6/1/23 @ 1055 – accurate?
CC: Fever
HPI: “This is a 4 y/o male who presented to the ER with fever and vomiting. Mother reports that patient started with vomiting on 5/28/23. No diarrhea, but mother reports constipation. The following day, he started with fever. No cough, nasal congestion, or difficulty breathing. [WTF?] Pt does attend daycare.”
Vitals @ 0730:
• T 100.4
• HR 177
• RR 28
• O2 100% on RA
PE:
• General: “appropriate, no apparent distress, not toxic appearing”
• Respiratory: “normal breath sounds, no distress”
• Abdomen: “normal bowel sounds, non-tender, soft”
Labs noted: Mycoplasma pneumoniae IgM non-reactive
Diagnosis, Assessment & Plan:
• “This is a 4 y/o male with pneumonia.”
• Plan:
o Admit to peds for obs
o Vitals Q4
o Continuous pulse ox
o Peds diet
o Tylenol/motrin PRN
o Rocephin IV
• “Pt with no respiratory distress or hypoxia since admission. Stable for d/c home on oral antibiotics. Return to ER if any concerning symptoms.”
• Signed at 1101 – so it appears this H&P was done at the same time as the discharge summary.
Further nursing notes:
1120 Vitals: T 36.9, HR 145, RR 26, O2 100%
1241: PIV discontinued
1243: time of discharge
• Discharge vitals: T 36.9, HR 145, RR 26, BP 117/66, O2 100% (these are all old)
o Discharged
Rx Cefdinir 250 mg/5 mL suspension, 5 mL PO daily x 10 days
• At some point this was apparently changed to Augmentin because Cefdinir was unavailable
To f/u w/ PCP in 2 days
- 6/3/2023: to ED at Lawnwood – initial greet time 2219:
o “Pt was brought to the ED 4 days ago for resp distress and admitted for pneumonia, sent home next day on Augmentin. Fever, cough, and congestion have persisted, and today pt developed diarrhea x3 and vomiting x1. Still seems to have trouble breathing.”
o ROS: Mom reports decreased appetite and activity, nasal congestion, cough, shortness of breath, diarrhea, vomiting, decreased urination
o Vitals @ 2216: O2 95% on RA, BP 109/68, T 38.1, HR 177, RR 22
o PE:
General: “Awake, alert, tired appearing”
Respiratory/Chest: “Atraumatic, tachypnea (RR 60s), Wheezing mild, Retractions moderate”
All else WNL
Clinical impression: Pneumonia.
• Secondary: Loculated pleural effusions.
o Labs:
Sodium 132 L
CO2 16 L
BUN 47 H
Calcium 8.0 L
Total Bili 4.3 H
AST 192 H (ALT 23 WNL)
WBCs 13.7 (WNL)
Hgb 8.1 L (Hct TNP)
Plt 124 L
RSV antigen, COVID-19, Influenza A negative
Influenza B positive
o CXR impression:
1. Opacification of the right upper and lower pleural spaces concerning for loculated pleural effusions. Cannot exclude loculated empyemas as the patient has a diagnosis of pneumonia.
2. Diffuse opacification of the right lung corresponds with pneumonia.
o CT chest w/ contrast impression:
1. Right upper lobe consolidative pneumonia is visualized, extending from the anterior right upper lobe towards the apex.
2. Parapneumonic effusion, which is loculated is visualized mostly within the lower pleural space, with the loculated portion extending anterolaterally.
3. Irregular appearing cystic spaces within the aerated left lower lobe adjacent to the pneumonia and pleural effusion.
o 0021: on FiO2 24, flow rate 20 (?)
o 0103: Pt accepted for transfer to Palms West for PICU
o 0225 Vitals: T 37.2, HR 156, RR 22, BP 106/57, O2 100% on HFNC, Flow rate 2
- 6/4/2023: Admitted Palms West
o Admitted to PICU
Seizures a few hours later --> intubated
Hgb 2.2, plt 51k
Coombs + IgG --> multiple transfusions, IVIG
o Septic shock w/ multi-organ dysfunction, acute respiratory failure, DIC, seizures 2/2 necrotizing pneumococcal pneumonia w/ right-sided parapneumonia empyema
o Stormy course
- 7/6/2023: discharged home on enalapril, amlodipine, clonidine
Files:
No questions yet!
Do you believe there might have been medical error?
The empyema was a critical part of this case that was not communicated to the receiving institution. Likewise the blood culture results were not communicated. SOP in receiving such a patient would be a page-by-page review of all the studies and summaries from the sending institution and a note to follow up on any un-resulted labs and tests. This is the case that is easiest to make, against both St. Lucie and Longwood. A harder case would be to prove that the admitting/discharging pediatrician misrepresented the appearance of the child at the time of discharge, although that may also be likely. The bottom line remains that a review of all available data on transfer is a bare minimum standard of care.
Do you believe there might have been causation (i.e. the medical error resulted in an injury)?
An effusion should have been monitored closely and likely drained and cultured. It should indicate broader antibiotic coverage, including coverage for MRSA such as with Vancomycin. Failure to track the progress of the effusion is clearly related to the patient's subsequent decompensation.
What makes you a good expert for this case?
I have been practicing pediatric hospital medicine for over five years and have extensive experience with designing and implementing clinical protocols based on available guidelines.
How often do you encounter cases similar to this one in your practice?
Community acquired pneumonia, daily. With effusion, perhaps annually. With florid sepsis, rarely, thankfully.
Do you believe there might have been medical error?
There was a failure to recognize and respond to a concerning lab value. The positive blood culture obtained at St. Lucie was not communicated to the staff at the Lawnwood emergency department or pediatric hospitalist. Based on the records available I am unsure if the St. Lucie emergency department failed to notify the Lawnwood staff, or the Lawnwood staff failed to follow up. It appears that the patient was given Ceftriaxone at St. Lucie, and Zithromax at Lawnwood. Based on the susceptibilities of the bacteria, Ceftriaxone and Zithromax were not appropriate antibiotics to treat the patient's bacteremia or pneumonia. In essence, this patient was discharged without appropriate treatment and returned to the emergency department in worse clinical condition.
Do you believe there might have been causation (i.e. the medical error resulted in an injury)?
The lack of appropriate antibiotics led to the patient developing septic shock and multi organ failure. If the medical team at Lawnwood knew about the highly resistant bacteria grown from the blood culture, they would have likely aggressively treated him with the proper antibiotic, and there would have been a different clinical outcome.
What makes you a good expert for this case?
I have been a pediatric hospitalist for 14 years, and have taken care of many children with community acquired pneumonia and bacteremia. I have been involved in a few malpractice cases, and continue to improve my skills. I am a great communicator, and am capable to writing bulletproof expert witness reports.
How often do you encounter cases similar to this one in your practice?
I have taken care of many children with pneumonia complicated with bacteremia. This is very common in my inpatient practice.
Do you believe there might have been medical error?
Thank you for the opportunity to comment on this case, Young children commonly present with vomiting, cough, and decreased oral intake due to bacterial pneumonia. Several features of the child whose case was presented suggest a sicker child than a routine case, however. These features include a mild-moderate right pleural effusion on imaging, a somewhat low serum sodium (probably due to SIADH), and ultimately a positive blood culture (probably fewer than 5% of children with bacterial pneumonia have a positive blood culture). However, a positive blood culture can in certain cases be extremely helpful because it can help identify the pathogen responsible (and its antibiotic sensitivities) without requiring an invasive test such as a bronchoscopy. Based on the information presented here, I strongly believe that due to the receiving institution's lack of knowledge of the blood culture/sensitivities result, the child was treated with the wrong antibiotics. Augmentin would not be expected to be effective in the case of ceftriaxone-resistant strep pneumoniae. There is a chance that even if given the correct antibiotic, the child would have continued to develop complications (such as empyema) but the chances would have been significantly lower had he been treated correctly.
Do you believe there might have been causation (i.e. the medical error resulted in an injury)?
Please see my explanation above. There has never been a study comparing the natural history of children with bacterial pneumonia treated with the correct antibiotic vs those treated incorrectly (this would be unethical), so there is no way to definitively put a number on how likely the child would have been to have had complications should he have been correctly treated. I have seen a number of children who have developed these complications despite being on the correct antibiotic, However, there was certainly a medical error and this probably cost the child at least several days in terms of illness progression.
What makes you a good expert for this case?
I am a board-certified Pediatric Hospitalist (and General Pediatrician) who has worked at a nationally recognized children's hospital for 18 years. I have served as an expert witness for a number of cases, both for the plaintiff and defense, and have significant deposition experience. I have published a number of research studies on how to improve systems of care to take better care of children and am a full professor of Pediatrics at a nationally known medical school (there are very few Pediatric Hospitalists in the US who are full professors). I have presented work regarding systems of care for children at many national conferences. I have won a variety of teaching and service awards, including by the American Academy of Pediatrics.
How often do you encounter cases similar to this one in your practice?
Very often, at least 5-10 cases per year.
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